Metformin may decrease vitamin B12 levels and increase levels of homo‐cysteine, leading to higher cardiovascular risk. In a trial where 196 patients received a mean dose of Metformin of 2.1g homocysteine increased by an average of 0.40 μmol and vitamin B12 decreased by 4.40 pmol.Like a couple of others mentioned, I was told to take a b-complex to offset what metformin depletes. In general, my fatigue before metformin was helped by taking a b12 supplement. I think is also depletes Vitamin D and sweet baby Jesus if my Vit D dips just a little bit I can't get out of bed and function as a human.Metformin is a drug that is being studied for its potential to treat liver fibrosis, a condition where the liver becomes stiff and scarred. This study found that metformin affects the mitochondria (the powerhouses of cells) in a certain type of liver cell called hepatic stellate cells (HSCs) and helps to decrease the severity of liver fibrosis.I like the smell of spirinolactone, it smells like mint. I take spironolactone, metformin, and bupropion SR and I have never noticed a smell with any them. I even get them all filled at the same time, my poor pharmacy tech.. Omg maybe if you ask your tech or pharmacist they might let you smell it.As a prediabetic, I never took metformin. Carnivore alone fixed all the issues related to pre-diabetes: debilitating frequent urination, coldness of the extremities, feeling cold all the time, reactive hypoglycemia, random sensation of tingling of the feet, numbness. FriedDuckEggs. • 2 yr. ago. Hi! I just started metformin Wednesday, so we’re twins! I have a 2000 mg rx, but doc told me to start at 500, up to 1000, up to 1500, up to 2000 basically once the smaller dose felt comfortable. I took 500 on Wednesday and Thursday and had no real issue other than kinda what you described. Takeaway. Metformin is used to help treat type 2 diabetes. Mild side effects, such as nausea, vomiting, and diarrhea, are common and go away with time. But, some …Like a couple of others mentioned, I was told to take a b-complex to offset what metformin depletes. In general, my fatigue before metformin was helped by taking a b12 supplement. I think is also depletes Vitamin D and sweet baby Jesus if my Vit D dips just a little bit I can't get out of bed and function as a human. Metformin doesn't really work that way, no. Metformin doesn't affects the food you eat. But, carbs aren't by definition bad. Whole plant based is a high carb diet, but often super successful in treating type 2 because of the type of food it focuses on. Reddit has raised a new funding round, totaling $250 million. This is the company’s Series E round of financing, and it comes hot on the heels of renewed public attention on the si...It’s just me who notices. Not sure if this is your experience, but those are my thoughts! I found that after a few months on Metformin that the symptoms of severe pms during the luteal phase resulted in me feeling more mood swingy. I now take more b vitamins to make up for what I suspect Metformin is depleting somewhat.Metformin was then used in a separate study to achieve the same effect without the need to fast. A human study used a small sample with a 7 day fast and reviewed 6 months later also showing positive results. Clemastine has shown improvement in ocular health in MS studies - which indicated remyelination at doses of 5.3mg daily.Well, that’s actually a big reason why the trial has been proposed: according to a recent study,1 metformin seems to extend lifespan, which is the ultimate acid test of intervention against aging. Specifically, it has been reported that diabetics taking metformin live longer, on average, than non-diabetics: in other words, that the overall ...Update: Got way worse this morning. Messaged the doc and he said to stop the glimepiride for now. New diagnosis, a little over a week in. My blood sugar is responding well to the metformin and glimepiride the doctor put me on, but I've noticed in the past couple days I've had a couple of 'black moods' - crying jags over silly things and the like - which usually …It sucks. metformin not only increase my back pain but also exhibit high amount of night time peeing. I usually pee up to 8 times a night to even more some night. But Once i sleep i have no problem getting back to it until next peeing session. yes I take metformin don't have trouble sleeping.Metformin and stomach issues. Hey! I was recently diagnosed with DT2 with an A1c 9.7 😢 doctor prescribed 2 gr of metformin daily and advised me to start gradually and now I’m taking the two pills however is making me sick with diarrhea and nausea, I noticed this when I started to take the second pill. I also had IBS before so it’s …When I first started metformin I immediately noticed I was full after 1 big meal. Notice a bit of weight loss only taking 500mg a day. Bumped up to 1000mg and I would wake up feeling so drained depressed and unmotivated. When taking 500 mg I was good but 1000 gave me those feelings. I know metformin blocks b12.Make sure you're taking it with food. Your doctor should have started you on a low dose to build your tolerance. For example, 500mg once a day for a week, then 500mg 2x a day. Then blood work after a certain amount of time to see if you need a higher dose. At that point, if increased, 1000mg in am, 500 at night for a week, then 1000mg 2x a day.However, after 1 month of treatment, a significant decrease in total, free, and bioavailable testosterone was observed in the metformin group compared with baseline levels (P <.05). No significant decrease was observed in the control group.”. Testosterone increases at first then drops after a month. After four months of diet and exercise I had lost 13 kg and was no longer prediabetic, so she took me off metformin. I continued to lose weight (15 more kg) unmedicated with normal sugar levels and controlled PCOS. I do believe that metformin helped me in the first part of my journey by managing my insulin resistance. Side effects included: extreme diarrhea, headaches, nausea, stomach pains, brain fog, a feeling of brain fuzziness (like pins and needles but sometimes sharper), and probably other things I've blocked out of my mind at this point because it was the worst month of my life. 14 votes, 30 comments. true.Side effects included: extreme diarrhea, headaches, nausea, stomach pains, brain fog, a feeling of brain fuzziness (like pins and needles but sometimes sharper), and probably other things I've blocked out of my mind at this point because it was the worst month of my life. 14 votes, 30 comments. true. Just recently diagnosed with PCOS and my Dr is putting me on Met, 500mg (ER) to assist with weightloss and PCOS symptoms. I am 5ft7 and 244lbs. I was on strict keto since January 2018 and all I could lose was 10lbs. Extremely frustrating. I would like to hear from people on 500mg and who are losing weight, with or without diet/excercise. Metformin was then used in a separate study to achieve the same effect without the need to fast. A human study used a small sample with a 7 day fast and reviewed 6 months later also showing positive results. Clemastine has shown improvement in ocular health in MS studies - which indicated remyelination at doses of 5.3mg daily.Using metformin alone, with a type of oral antidiabetic medicine called a sulfonylurea, or with insulin, will help to lower blood sugar when it is too high and ...It’s just me who notices. Not sure if this is your experience, but those are my thoughts! I found that after a few months on Metformin that the symptoms of severe pms during the luteal phase resulted in me feeling more mood swingy. I now take more b vitamins to make up for what I suspect Metformin is depleting somewhat.Insulin kicks in when it starts approaching the max, and is absorbed well enough that the blood sugar gets used and goes back down. Pre-diabetes means your system is floating above that at like 100-120 or so. You are still utilizing insulin at …Side effects included: extreme diarrhea, headaches, nausea, stomach pains, brain fog, a feeling of brain fuzziness (like pins and needles but sometimes sharper), and probably other things I've blocked out of my mind at this point because it was the worst month of my life. 14 votes, 30 comments. true.Metformin will not cause a weight loss, it will merely make the fat loss possible. It's up to you to do dietary changes to lose weight. Look up in this subreddit what exactly to do, but basically - a lot of fibre and greens, 1-1.3g of protein per kg of body mass, some healthy fats (20g?), no carbs added if possible.I am currently on 100mg of Topamax for migraine / weight loss prevention and 1000mg Metformin for Insulin resistant PCOS. So far, I have lost 15lbs with this combination! I actually haven’t been taking the full 1000mg. So I’ve just been doing 500mg for now. because I was worried about the rare side affect of lactic acidosis which I’ve ...Heck you could even be getting more diabetic and the dose of metformin you're on could be not working anymore and that could be making you tired. That would show in an A1C test. FXOjafar • 2 yr. ago. Have you been waking around …Are you looking for an effective way to boost traffic to your website? Look no further than Reddit.com. With millions of active users and countless communities, Reddit offers a uni...May 11, 2021. #1. Hi all, winder if anyone can help me. I have been diabetic for 5 years and been diet controlled until recently. They have out me on Metformin and ever since I have … Metformin and Bodybuilding. I was listening to a bodybuilding podcast and one guy was saying that he was taking Metformin during contest prep and it helped him stay full. Metformin is an oral drug used typically in type 2 diabetics in order to lower blood sugar by increasing insulin sensitivity and allowing more glucose to be used in the muscles. Metformin doesn't really work that way, no. Metformin doesn't affects the food you eat. But, carbs aren't by definition bad. Whole plant based is a high carb diet, but often super successful in treating type 2 because of the type of food it focuses on. Metformin doesn't really work that way, no. Metformin doesn't affects the food you eat. But, carbs aren't by definition bad. Whole plant based is a high carb diet, but often super successful in treating type 2 because of the type of food it focuses on. Increase your carb amount and try to eat those whole grains and vegetables. If you’re getting nausea, try an antihistamine to make sure it’s not a psychological kinda nausea, or lower your dosage of met and increase it slower. If you’re getting heart burn, reflux, etc, limit your citrus and acidic foods. Undervalued Reddit stocks continue to attract attention as we head into the new year. Here are seven for your perusal. Tough economic climates are a great time for value investors ...Long & boring story short, I’ve been on metformin just under a week - and I’ve had awful all-body itching and hives twice. Each time just after taking metformin. I am going to speak to my nurse ASAP, I’m not seeking medical advice. Just wondering what people’s experiences are ☺️. Commonly causes gastro issues.You do need to make lifestyle changes with or without metformin, but personally if I were you, I would take metformin because your insulin is through the roof. A healthy fasting insulin level is five or under. Your HOMA-IR is also very concerning; healthy is around one and over three is significant IR. So I think you just want to get things ...Metformin is designed to help the insulin you are currently making, absorb into the cells. Since Type 1s make ZERO insulin, it’s a waste to take it. Type 2 benefits as their body still produces insulin yet struggles to process it, enter Metformin.It also has been documented to help with fertility and healthy pregnancy outcomes in PCOS populations. Berberine hasn’t been quite as extensively studied as inositol but there growing research on it also bodes well for its efficacy compared to metformin. It also has been found to be less harsh in terms of side-effects. Yes, it goes away almost completely. I’m on 2000 mg but it took almost a month to work up to that and a few month after that until the symptoms really eased up. Definitely go with the extended release formula and be patient. Good luck!! vivagypsy • 5 yr. ago. I had some GI upset last week which was week 1. So while it may seem like it’s the Metformin, small changes in your diet will make you lose weight. Also, a lot of T2 start at a pretty heavy weight, so even a small dietary change can lead to weight loss. I’ve been on Metformin for 2 years now. PCOS also. Lost about 15lbs from a combination of diet and metformin. The tummy issues can vary if you have a generic form, from my experience. I found that out the not-so-fun way. When I first started Metformin (also for the damn PCOS), I lost about 15lbs, but that was it. Metabolic abnormalities, including insulin resistance and dyslipidemia (particularly low high-density lipoprotein levels), frequently coexist with obesity.r/InsulinResistance. r/InsulinResistance. Discussions about defeating Insulin Resistance, the cause of most disease. MembersOnline. •. Comfortable_You_3280. Metformin and Cravings. I was diagnosed with PCOS and insulin resistance last week, and I've been taking 500mg metformin since Saturday. Since then my constant insatiable carb and sugar ... Berberine seems better for directly working on increasing insulin sensitivity, which then helps lower blood sugar indirectly. Metformin on the other hand seems to lower blood sugar better than berberine, though it may not be as good at increasing insulin sensitivity directly. I still feel low key hunger on metformin, though it's still better ... Metformin is an FDA-approved antidiabetic agent that manages high blood sugar levels in type 2 diabetes patients. It reduces glucose absorption from the intestines, …xxthelightxx • 1 mo. ago. Metformin is used to treat high glucose numbers, he might just be trying to lower his glucose to burn more fat. It has serious gut issues when imporperly used. UghAnotherMillennial • 1 mo. ago. It can also block b12 absorption in some cases. Bella_Climbs • 1 mo. ago.Aug 16, 2566 BE ... Maybe time for a new doctor. What are you doing diet and exercise wise to stop your a1c from going higher? Three successive A1Cs that are ...Oct 7, 2565 BE ... Metformin was a godsend for me, I was never able to lose weight before it, now I've lost 40lb over 10 months! I got nausea and diarrhea that ... The studies he's done show that there are several things that have a significant impact on this kind of healthy longevity - including growth hormone, cholesterol, and mitochondrial peptides. He also suggests that metformin, a diabetes medication, could be a powerful tool for slowing down age-related decline. Hi Reddit, (to whom I owe the greatest of debts for the incredible support since my Type 2 dx.) ... Metformin is a slow/long acting drug: it has very little immediate impact on your blood glucose levels. So you can take it whenever you like: ...Berberine is a dupe for metformin so I think it’s worth a shot. Metformin did not help my hair loss. It has helped with some reactive hypoglycemia. I tried Spiro! Zero Success it gave me the dread shed and I stopped it a few days ago after 6 …View community ranking In the Top 1% of largest communities on Reddit. Metformin and inhibition of gluconeogenesis: is it safe ... "This redox-dependent mechanism would also explain why metformin treatment is rarely associated with hypoglycemia given that gluconeogenesis will never be totally inhibited. "I take 1000 in the morning, and 1000 at night. The metformin half life in your bloodstream will remain the same no matter what time you take it. The difference will be how quickly and how completely your body absorbs it depending upon if your stomach is full or empty. According to the FDA, it is absorbed slightly faster and with slightly higher ...Type 2. I wanted to share my personal experience with Ozempic vs. Metformin to see if anyone else has similar results. For a couple of years I'd been taking Metformin and had good results. In particular, with regular exercise, normal weight, and fairly strict control of my diet, I had achieved an A1C level of 6.4 as of December 2022.let me start by saying I take a crap ton of medications. Mostly for MCAS and as a former nurse practitioner, I believe that most MCAS patients will need medications to control symptoms. That said, my stomach symptoms of MCAS did get worse on Metformin. I say give it a try. You can always stop taking it and it will leave your system pretty quickly.Learn about metformin, a medication for type 2 diabetes that improves insulin sensitivity and lowers blood sugar levels. Find out how it works, its benefits and risks, …Tried getting off metformin after the first 2 weeks on 2.5 and the constipation nearly killed me. So my PCP and I agreed that half dosage might be better for awhile. No bad side effects until I bumped up to 7.5 this month; nausea, constipation, insomnia. All in all, MJ and metformin work for me!!METFORMIN AND BERBERINE COMPARISON. Been on metformin for about a fortnight and built to one tablet in the AM and one in the PM now seem to be getting headaches every day. Looked into Berberine as a natural alternative, seems like its got general good reviews. Is there anyone out there who has used berberine and …From what I've read, viewed and experienced, it's normally an incremental dosage. First week, 500mg, second, 1000mg, third to 1500 and fourth to 2000 with each week checking for adverse side effects reporting negatives to your doc. Regardless, always check with your doctor on dosages and side effects as well as interactions with currently ...Hi all, I’m 27 f in Australia with constant weight issue. PCOS since young and been on the pill since 16years old. I’ve had constant weight fluctuations, with the only thing ever working was a really strict Keto diet, which is not sustainable. I’m looking at Saxenda, Contrave and Metformin, or even a combination of 2.Metformin doesnt decrease/increase insulin secretion. What it does is that it changes the response of tissues to insulin. Its an insulin sensitizer, meaning it will cause tissues to take up more glucose from blood. This is why its primary use is in type2 diabetes, these people have tissues that are "insulin resistant".You do need to make lifestyle changes with or without metformin, but personally if I were you, I would take metformin because your insulin is through the roof. A healthy fasting insulin level is five or under. Your HOMA-IR is also very concerning; healthy is around one and over three is significant IR. So I think you just want to get things ...reply. My doc suggested taking Metamucil two hours after the metformin to help with GI issues. It worked. Nah, I take it twice a day and it's fine. Been on it for 20+ years. No side effects that I’ve noticed. I went from 500 mg a day to 2000 mg in a day in one week. I am the opposite, now I can't go the bathroom.Metformin is a common drug used to treat insulin resistance in folks with diabetes, PCOS, and other conditions that may affect blood sugar. It is not a weight loss drug, it is a drug used to control blood sugar. The times it has come up, Aubrey has basically just said how terrible it is because of the side effects, which can be admittedly rough ... ADMIN MOD. [Compound Experience Saturday] Metformin. Compounds. For those unaware, each week we have a specific steroid or PED up for discussion. This week we are discussing Metformin. The goal of these threads is to generate discussion about the posted compound and get a wide variety of user experiences and feedback about it. I like the smell of spirinolactone, it smells like mint. I take spironolactone, metformin, and bupropion SR and I have never noticed a smell with any them. I even get them all filled at the same time, my poor pharmacy tech.. Omg maybe if you ask your tech or pharmacist they might let you smell it.Discover how the soon-to-be-released Reddit developer tools and platform will offer devs the opportunity to create site extensions and more. Trusted by business builders worldwide,...I was diagnosed with Type 2 diabetes three years ago, and was prescribed 1000 mg Metformin in the morning and night. My A1C number was 8.0 (fasting glucose 180) ...I hate how reddit just downvotes dissenting voices away and it really removes the space for discussion. Eta - I remain gently skeptical of metformin as it seems to be the latest buzz miracle drug for weight loss for celebrities especially in the usa, but i remain open-minded to seeeing how it all pans out :) thx for reply.Dec 10, 2566 BE ... I think the side effects of metformin are drastically overblown. A case of the minority of experiences having a very loud voice. Other than the ...Feb 1, 2565 BE ... Embaressed to say I have no idea how to use reddit but here I am. I'm trying to adopt/borrow a diabetic cat. I tried an online pharmacy but it ...It took me a few months off metformin plus weekly B12 injections to get my levels back to normal. I feel so much more energized and alert now. shamanixx. • 6 yr. ago. Now that you mention it, I really do remember experiencing brain fog the year I was on Metformin. Its crazy to see this thread!Reddit is a popular social media platform that boasts millions of active users. With its vast user base and diverse communities, it presents a unique opportunity for businesses to ...Metformin is not a direct route to increase fertility. It does help regulate your insulin which may result in a higher chance of pregnancy. I've been on it since 2015 and nothing hashappened to me expect a couple of stomach emergencies. Do your best to keep your blood sugars stable, inflammation down, and hydrated.Metformin is designed to help the insulin you are currently making, absorb into the cells. Since Type 1s make ZERO insulin, it’s a waste to take it. Type 2 benefits as their body still produces insulin yet struggles to process it, enter Metformin.
Alternative to metformin, preferably injectables. Prediabetic. Hi all, I was just diagnosed with pre-diabetes, and after a week on Metformin I can't tolerate it. The acid reflux was getting better until last night, when it came back with a vengeance, along with really bad nausea, stomach pain, a terrible metallic taste and a sore tongue (which ... . League of legends yordles
The literature suggests Metformin is a useful, simple option for antipsyhotic induced gain weight. My question is, do you use it in your practice? And if so, when do you start it? When you notice the patient is gaining weight or preemptively when you initiate an antipsyhotic known for this? (eg. olanzapine) Sort by: Add a Comment. GI problems started as soon as I was taking the 2 pills of metformin a day + paxlovid. Inhad the worst diarrhea and was nauseous the entire day. So I stopped metformin. I ended up getting covid rebound 4 days after my last dose of paxlovid. I do not know if metformin helps prevent rebounds. If they did and I knew it, I would've continued the ... Aug 16, 2566 BE ... Maybe time for a new doctor. What are you doing diet and exercise wise to stop your a1c from going higher? Three successive A1Cs that are ...So while it may seem like it’s the Metformin, small changes in your diet will make you lose weight. Also, a lot of T2 start at a pretty heavy weight, so even a small dietary change can lead to weight loss. I’ve been on Metformin for 2 years now. PCOS also. Lost about 15lbs from a combination of diet and metformin.Apr 24, 2565 BE ... About a week for me. 1000mg x 2 a day. Taking with food helps. But it was a week for hell and it will still happen if I eat a lot of fruit / ...Just recently diagnosed with PCOS and my Dr is putting me on Met, 500mg (ER) to assist with weightloss and PCOS symptoms. I am 5ft7 and 244lbs. I was on strict keto since January 2018 and all I could lose was 10lbs. Extremely frustrating. I would like to hear from people on 500mg and who are losing weight, with or without …Sep 22, 2566 BE ... ... Reddit · Wechat. Abstract. Epilepsy is a chronic neurological disease characterized by recurrent seizures. Epilepsy is observed as a well ...Things that control blood glucose via the same mechanisms will have similar hormesis-reducing effects. Although the AMPK activation from berberine is less than metformin. I personally use and really like berberine/DHB. Haven't noticed any decreases in endurance or lactate tolerance as is commonly reported with metformin.In a short GnRH-antagonist protocol, metformin may reduce live birth rates, although we are uncertain about the effect of metformin on clinical pregnancy rate. Metformin may reduce the incidence of OHSS but may result in a higher incidence of side effects. We are uncertain of the effect of metformin on miscarriage rate per woman.IR usually needs to be taken throughout the day, SR is fine taken morning and night. Thank you! Definitely take it with a meal! Never on a empty stomach and try drinking lots of water afterwards! It can cause lots of stomach pain/ache for the first weeks to a month that you take it so take it easy. Thank you!Been on Metformin for 4 years- consistent diarrhea and loose stools. I was diagnosed as type 2 in April 2015. I cannot honestly remember the last time I had a normal stool. I consistently either have diarrhea or very loose stools. My doctor prescribed me 1000mg twice daily and I'm fairly certain they're NOT the extended release as my medicine ...Also PCOS and nondiabetic. The metformin is used to help regulate my hormones/cycles. It's been a godsend. Just make sure to know the signs and symptoms of hypoglycemia- the meds main job is to help lower blood sugar, if it drops too low it can be dangerous- I've had an easier time regulating it with the protein on keto.I take 1000 in the morning, and 1000 at night. The metformin half life in your bloodstream will remain the same no matter what time you take it. The difference will be how quickly and how completely your body absorbs it depending upon if your stomach is full or empty. According to the FDA, it is absorbed slightly faster and with slightly higher ...healthyhealthhealth. • 5 yr. ago. I'm prediabetic but also on Metformin, and this is exactly how I've been feeling. I've been repulsed by all sorts of foods I used to enjoy and it's making me sad. Like I literally feel like I'm going to throw up with certain foods, and these are foods I would frequently eat. I thought I was the only one.Dec 25, 2565 BE ... Metformin is not like ozempic. It kinda works as a mild appetite suppressant. You have to put in the work to. Intermittent fasting n low calorie ....